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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF11 All Species: 7.88
Human Site: S1017 Identified Species: 10.83
UniProt: P52732 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52732 NP_004514.2 1056 119159 S1017 P F F Q H K K S H G K D K E N
Chimpanzee Pan troglodytes XP_507923 1056 119132 S1017 P F F Q H K K S H G K D K E N
Rhesus Macaque Macaca mulatta XP_001087644 853 96218 Q817 K I S Q E I E Q R C E S L N T
Dog Lupus familis XP_534964 1334 149091 K1298 I P F F Q H K K S H G K D K E
Cat Felis silvestris
Mouse Mus musculus Q6P9P6 1052 118008 P1013 P F F Q R K K P H G K D K E N
Rat Rattus norvegicus O55165 796 89797 R760 R P S T S K V R K S R S W C Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 P1161 F Q P V Y S P P T M K V L K D
Frog Xenopus laevis P28025 1060 119314 A1022 R F F Q Q K K A L R K E K E N
Zebra Danio Brachydanio rerio NP_775368 955 106984 V919 N T Q A L D T V H N F I S S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46863 1066 121145 T1017 T V K R G C G T T R N S N S N
Honey Bee Apis mellifera XP_623508 706 80766 P670 K K L I K T S P H G R L L K K
Nematode Worm Caenorhab. elegans P46873 699 78760 K663 S K S L F P S K T P T F D G L
Sea Urchin Strong. purpuratus P46872 699 78679 Y663 L E G G G M K Y K P S Q G K S
Poplar Tree Populus trichocarpa XP_002314206 1066 119757 T1019 A S I E E L R T P A F E E L L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 P1004 P Q Q L T R S P L S Q L K F S
Baker's Yeast Sacchar. cerevisiae P28742 1111 125776 K1067 S A K S N R S K T L P N T E G
Red Bread Mold Neurospora crassa P48467 928 102392 R892 S R I A K P L R G G G D A V A
Conservation
Percent
Protein Identity: 100 99.8 77.5 69.3 N.A. 79.7 23.3 N.A. N.A. 25.3 56.2 47.7 N.A. 33.5 37.1 27.4 29.2
Protein Similarity: 100 99.9 79 73.8 N.A. 89 40.4 N.A. N.A. 43.5 72.7 63.9 N.A. 55.4 52 42.5 42.8
P-Site Identity: 100 100 6.6 13.3 N.A. 86.6 6.6 N.A. N.A. 6.6 60 6.6 N.A. 6.6 13.3 0 6.6
P-Site Similarity: 100 100 20 20 N.A. 86.6 13.3 N.A. N.A. 26.6 73.3 6.6 N.A. 20 26.6 0 20
Percent
Protein Identity: 32.9 N.A. N.A. 31.9 27.2 27.5
Protein Similarity: 52.3 N.A. N.A. 51.5 48.6 45.5
P-Site Identity: 0 N.A. N.A. 13.3 6.6 13.3
P-Site Similarity: 33.3 N.A. N.A. 33.3 26.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 6 0 12 0 0 0 6 0 6 0 0 6 0 6 % A
% Cys: 0 0 0 0 0 6 0 0 0 6 0 0 0 6 0 % C
% Asp: 0 0 0 0 0 6 0 0 0 0 0 24 12 0 6 % D
% Glu: 0 6 0 6 12 0 6 0 0 0 6 12 6 30 12 % E
% Phe: 6 24 30 6 6 0 0 0 0 0 12 6 0 6 0 % F
% Gly: 0 0 6 6 12 0 6 0 6 30 12 0 6 6 6 % G
% His: 0 0 0 0 12 6 0 0 30 6 0 0 0 0 0 % H
% Ile: 6 6 12 6 0 6 0 0 0 0 0 6 0 0 0 % I
% Lys: 12 12 12 0 12 30 36 18 12 0 30 6 30 24 6 % K
% Leu: 6 0 6 12 6 6 6 0 12 6 0 12 18 6 12 % L
% Met: 0 0 0 0 0 6 0 0 0 6 0 0 0 0 0 % M
% Asn: 6 0 0 0 6 0 0 0 0 6 6 6 6 6 30 % N
% Pro: 24 12 6 0 0 12 6 24 6 12 6 0 0 0 0 % P
% Gln: 0 12 12 30 12 0 0 6 0 0 6 6 0 0 6 % Q
% Arg: 12 6 0 6 6 12 6 12 6 12 12 0 0 0 0 % R
% Ser: 18 6 18 6 6 6 24 12 6 12 6 18 6 12 12 % S
% Thr: 6 6 0 6 6 6 6 12 24 0 6 0 6 0 6 % T
% Val: 0 6 0 6 0 0 6 6 0 0 0 6 0 6 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 % W
% Tyr: 0 0 0 0 6 0 0 6 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _